Tokushima University · Faculty of Bioresource Sciences, Course of Bioproduction Systems · 准教授

Research keywordsGryllus bimaculatus・insect leg regeneration・developmental genetics・JAK-STAT signalling・fibroblast growth factor receptor・wing patterning・body color variation・embryonic asymmetry

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• Bone morphogenetic protein signaling in distal patterning and intercalation during leg regeneration of the cricket, Gryllus bimaculatus.
• Molecular mechanisms of limb regeneration: insights from regenerating legs of the cricket Gryllus bimaculatus.
• The mesenchymal factor, FGF10, initiates and maintains the outgrowth of the chick limb bud through interaction with FGF8, an apical ectodermal factor
• Myoglianin is a crucial factor for the transition to the juvenile hormone-dependent phase during hemimetabolous nymphal development

• 不完全変態昆虫モデルシステムを用いた後胚期形態形成の制御機構解明
• TALEN法により疾患ゲノムを修復したiPS細胞を用いた自家臓器再生技術開発
• 昆虫脚再生における幹細胞群形成の時空間的制御機構の解明
• 細胞老化誘導に関わる酸化ストレス発生の分子機構の解明と関連microRNAの同定

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