Tokushima University · Graduate School of Sciences and Technology for Innovation · 准教授

Research keywords分子生物学・細菌学（含真菌学）・構造生物化学

Research fields細菌学

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• Derepression of Salmonella pathogenicity island 1 genes within macrophages leads to rapid apoptosis via caspase-1- and caspase-3-dependent pathways
• The DnaK/DnaJ chaperone machinery of Salmonella enterica serovar typhimurium is essential for invasion of epithelial cells and survival within macrophages, leading to systemic infection
• A LACTOCOCCUS-LACTIS GENE ENCODES A MEMBRANE-PROTEIN WITH PUTATIVE ATPASE ACTIVITY THAT IS HOMOLOGOUS TO THE ESSENTIAL ESCHERICHIA-COLI FTSH GENE-PRODUCT
• Identification of mutations resulting in derepression of the intermedilysin gene by sequential mutagenesis of its promoter region in Streptococcus intermedius.

• AAAプロテアーゼによる腸管病原性大腸菌の病原因子発現調節機構
• 2重安全機構を採用した癌指向性の細胞内崩壊性リポソームによる癌治療技術の開発
• 細菌感染における生体防御機構エスケープ因子としてのストレス蛋白の解析
• 口腔連鎖球菌ストレプトコッカス・インターメディウスのヒト特異的感染現象の分子機構

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