Tokushima University · Faculty of Dentistry · 教授

Research keywordsstreptococcal pathogenesis・antimicrobial resistance・pili assembly・oral biofilms・neutrophil traps・antibacterial nanoparticles

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• Competence-induced protein Ccs4 facilitates pneumococcal invasion into brain tissue and virulence in meningitis
• Streptococcus sanguinis が産生する細胞壁架橋型ヌクレアーゼによる免疫回避機構
• Streptococcus sanguinis が産生する過酸化水素は NETs 形成を誘導する
• Characterization of Lachnoanaerobaculum sanguinis sp. nov., isolated from a blood culture of an acute myeloid leukemia patient with chemotherapy-related bacteremia

• 肺炎球菌の細胞壁分解能が病態形成と薬剤耐性獲得に果たす役割の解明
• 菌体表層に存在する線維状タンパク質重合体の会合と抗原性がもたらす病原性の探索
• 細菌性髄膜炎の発症につながる新規細菌伝播経路と感染制御法の探索
• Ａ群レンサ球菌ｎｃＲＮＡによる病原性調節機構の解析

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