Tokushima University · Faculty of Medicine · 教授

Research keywords胸腺・自己免疫疾患・Aire・Major histocompatibility complex

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• Unc93B1 Restricts Systemic Lethal Inflammation by Orchestrating Toll-like Receptor 7 and 9 Trafficking
• 巨細胞性心筋炎の発症には自己免疫調節遺伝子(AIRE)の発現亢進が介在する(Development of giant cell myocarditis through augmented expression of autoimmune regulator(AIRE))
• Mode of Tolerance Induction and Requirement for Aire Are Governed by the Cell Types That Express Self-Antigen and Those That Present Antigen.
• Revisiting Aire and tissue-restricted antigens at single-cell resolution.

• 臓器特異的自己免疫疾患の病態解明による慢性炎症制御法の開発2011
• ノックアウトマウスを用いたMHC領域内non-HLA遺伝子機能の解析(疾患感受性遺伝子の検索)
• 接触性過敏反応の病態におけるリンホトキシンの役割
• 2本鎖RNAに対する宿主応答機構の解析

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