Josai University · Department of Pharmacy / Faculty of Pharmaceutical Sciences

Research keywordsmedicinal chemistry・monoamine oxidase B inhibitors・styrylchromones・1,3-dioxin-4-ones・asymmetric aldol synthesis・polyamine oxidase・neuroprotective natural products

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• Cytotoxic activity of benzothiepins against human oral tumor cell lines
• A new g-butenolide glycoside from the root of Styphnolobium japonicum
• Formation of spermidine or norspermidine from synthetic diacetylpolyamines by acetylpolyamine oxidase in cultured cells
• Pentamines as Substrate for Human Spermine Oxidase

• 食品成分中のポリアミンによる腸管での消化・吸収の修飾
• 食品成分の腸管機能修飾に伴う免疫応答への影響
• 食品成分中のポリアミンによる腸管での消化・吸収の修飾
• タンパク質のコンホメーション変化を指標にするプロテオーム解析

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