Josai University · Department of Pharmacy / Faculty of Pharmaceutical Sciences · 教授

Research keywords薬化学・ジヒドロピリミジン・ビギネリ反応・抗増殖活性・食物薬物相互作用

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• Signal transduction mechanism for potentiation by alpha(1)- and beta(2)-adrenoceptor agonists of L-ascorbic acid-induced DNA synthesis and proliferation in primary cultures of adult rat hepatocytes
• Synthesis of 4,4-Disubstituted 3,4-Dihydropyrimidine-2(1H)-ones and -thiones, The Corresponding Products of Biginelli Reaction Using Ketone, and Their Antiproliferative Effect on HL-60 Cells.論文
• Clofibric acid increases the formation of oleic acid in endoplasmic reticulum of the liver of rats.
• Evidence that glyceraldehyde-3-phosphate dehydrogenase is involved in age-induced apoptosis in mature cerebellar neurons in culture

• Molecular mechanisms of neuronal differentiation, survival and cell death
• 神経細胞の分化・生存及び細胞死の分子機構
• 新規3-スチリルクロモン誘導体の口腔癌治療薬としての可能性に関する基礎研究
• Pharmacological examination on the interaction of foods and drugs

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