Institute of Science Tokyo · Institute for Advanced Studies

Research keywordsliver organoids・induced pluripotent stem cells・regenerative medicine・hepatoblastoma・steatotic liver disease・kidney replacement・organoid vascularization・gene-edited imaging

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• Kinoshita Y, Kobayashi E, Matsui K, Inage Y, Morimoto K, Yamamoto S, Iwai S, Kitada K, Iwasawa K, Saito Y, Fujimoto T, Matsumoto K, Nagamori S, Nishiyama A, Kume H, Takebe T, Yokoo T, Yamanaka S.. Life-supporting functional kidney replacement by integration of embryonic metanephros-bladder composite tissue transplants Kidney International. 2025.03;2025
• Rezvani M, Quach S, Lewis K, Saiki N, Xue C, Kimura M, Iwasawa K, Weihs J, Elzobair T, Al Reza H, Cai Y, Zhang R, Milton Y, Chaturvedi P, Thorner K, Nayak RC, Munera J, Kramer P, Davis BR, Balamurugan AN, Ahmed YA, Finke M, Behncke RY, Guillot A, Hägerling R, Polansky JK, Bufler P, Cancelas JA, Zorn AM, Wells JM, Yoshimoto M, Takebe T.. Modeling immune lineage co-development in human pluripotent stem cell-derived liver organoids Journal of Hepatology. 2025.12;2025
• Hirai A, Yoneyama Y, Assi I, Osonoi S, Sakai S, Ohtsu K, Takebe T.. Modeling Transmembrane 6 Superfamily Member 2 p.Glu167Lys-associated Steatotic Liver Disease Using Androgen-treated Human Induced Pluripotent Stem Cell-derived Hepatocyte-like Cells Gastro Hep Adv. 2025.08;2025
• Tominaga K, Kechele DO, Sanchez JG, Vales S, Jurickova I, Roman L, Asai A, Enriquez JR, McCauley HA, Kishimoto K, Iwasawa K, Singh A, Horio Y, Múnera JO, Takebe T, Zorn AM, Helmrath MA, Denson LA, Wells JM.. Deriving human intestinal organoids with functional tissue-resident macrophages all from pluripotent stem cells Cellular and Molecular Gastroenterology and Hepatology. 2025.01;2025

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