Institute of Science Tokyo · Institute for Advanced Studies

Research keywordsTDP 43・antisense oligonucleotides・autophagy・amphisome lysosome fusion・TFEB activation・lysosomal damage response・Atg9A trafficking・BECN1 dynamics

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• Sustained therapeutic benefits by transient reduction of TDP-43 using ENA-modified antisense oligonucleotides in ALS/FTD mice.2023 · Molecular therapy. Nucleic acids 31 353 - 366 2023年3月
• PACSIN1 is indispensable for amphisome-lysosome fusion during basal autophagy and subsets of selective autophagy.2022 · PLoS genetics 18 ( 6 ) e1010264 2022年6月
• Novel insights into the molecular mechanism of amphisome-lysosome fusion2022 · Autophagy Reports 1 ( 1 ) 542 - 545 2022年12月
• Author Correction: LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury.2022 · Nature cell biology 24 ( 11 ) 1677 - 1679 2022年11月

• 体液恒常性維持におけるオートファジーの役割2024 · 研究課題/領域番号： 24K18109 2024年4月 - 2027年3月

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