Institute of Science Tokyo · Institute for Advanced Studies

Research keywordsembryonic stem cell differentiation・human iPSC disease modeling・GJB2-related deafness・T-cell immunometabolism・primitive streak formation・autoimmune neuroinflammation・ceramide signaling・gap junction genetics

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• Jing Pu, Satoshi Kofuji, Yoshimi Okamoto-Uchida, Keiko Danzaki, Ruoxing Yu, Akira Suzuki, Satoshi Kitajima, Hiroshi Nishina. Lethal Phenotype-Based Database Screening Identifies Ceramide as a Negative Regulator of Primitive Streak Formation Stem Cells. 2023;2023
• Yazan Alwarawrah, Keiko Danzaki, Amanda G Nichols, Brian E Fee, Cheryl Bock, Gary Kucera, Laura P Hale, Gregory A Taylor, Nancie J MacIver. Irgm1 regulates metabolism and function in T cell subsets. Scientific Reports. 2022.01; 12 (1): 850. ( PubMed , DOI )2022
• Ichiro Fukunaga, Yoko Oe, Keiko Danzaki, Sayaka Ohta, Cheng Chen, Kyoko Shirai, Atsushi Kawano, Katsuhisa Ikeda, Kazusaku Kamiya. Modeling gap junction beta 2 gene-related deafness with human iPSC. Human Molecular Genetics. 2021.07; 30 (15): 1429-1442. ( PubMed , DOI )2021
• M Elizabeth Deerhake, Keiko Danzaki, Makoto Inoue, Emre D Cardakli, Toshiaki Nonaka, Nupur Aggarwal, William E Barclay, Ru-Rong Ji, Mari L Shinohara. Dectin-1 limits autoimmune neuroinflammation and promotes myeloid cell-astrocyte crosstalk via Card9-independent expression of Oncostatin M. Immunity. 2021.03; 54 (3): 484-498.e8. ( PubMed , DOI )2021

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