Institute of Science Tokyo · Graduate School of Medical and Dental Sciences · 准教授

Research keywords遺伝性腎疾患・慢性腎臓病エネルギー代謝・WNK-NCCシグナル・常染色体顕性尿細管間質性腎疾患・Gitelman症候群・SLC5A2腎性糖尿・AVPR2腎性尿崩症・腎メタボローム解析・尿中ウロモジュリン・食塩感受性高血圧

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• Hisazumi Matsuki, Shintaro Mandai*, Hiroki Shiwaku, Takaaki Koide, Naohiro Takahashi, Tomoki Yanagi, Shunsuke Inaba, Saaya Ida, Tamami Fujiki, Yutaro Mori, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Soichiro Iimori, Eisei Sohara, Hidehiko Takahashi, Shinichi Uchida. Chronic kidney disease causes blood-brain barrier breakdown via urea-activated matrix metalloproteinase-2 and insolubility of tau protein. Aging (Albany NY). 2023.10; 15 ( PubMed , DOI )2023
• Yanagawa H, Hara Y, Ando F, Suzuki S, Fujiki T, Oikawa D, Yui N, Mandai S, Mori Y, Susa K, Mori T, Sohara E, Tokunaga F, Uchida S. LRBA signalosomes activate vasopressin-induced AQP2 trafficking at recycling endosomes. The Journal of physiology. 2023.12; 601 (23): 5437-5451. ( PubMed , DOI )2023
• Shintaro Mandai, Takaaki Koide, Tamami Fujiki, Yutaro Mori, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Soichiro Iimori, Shotaro Naito, Eisei Sohara, Shinichi Uchida, Kiyohide Fushimi, Tatemitsu Rai. Association of Admission Functional Status and Body Mass Index with Mortality in Patients Receiving Chronic Dialysis: A Nationwide Observational Cohort Study. JMA J. 2023.10; 6 (4): 404-413. ( PubMed , DOI )2023
• 森 崇寧, 蘇原 映誠. 【腎臓病の最新診療】CKDに潜在する遺伝性腎疾患の重要性 日本内科学会雑誌. 2023.05; 112 (5): 799-804. ( 医中誌 )2023

• エネルギー代謝に注目した慢性腎臓病の進展メカニズムと臓器連関についての研究
• AMPKシグナルを基軸とした尿細管上皮細胞修復障害の解明と治療戦略
• エネルギー感知機構の破綻による慢性腎臓病の線維化進行機序解明と治療法開発
• 腎臓における水電解質輸送の異常と疾患

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