Institute of Science Tokyo · Graduate School of Medical and Dental Sciences · 助教

Research keywordsoral cancer・tumor microenvironment・epithelial-mesenchymal transition・TGF-beta signaling・cancer metastasis・microfluidic tumor model・circulating tumor cell clusters

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• Matsunaga, YT; Ikeda, Y; Suehiro, J; Oshima, H; Takahashi, K; Watabe, T; Oshima, M. Tumor-microvessel model reveals circulating tumor cell cluster formation and intravasation dynamics CANCER SCIENCE. 2025.01; 116 1308.2025
• Ai Watanabe, Jin Lu, Kai Ishihara, Sadahiro Iwabuchi, Kazuchika Ohno, Shinichi Hashimoto, Takahiro Asakage, Kazuki Takahashi, Katarzyna A Podyma-Inoue, Tetsuro Watabe. UBE2T promotes epithelial-mesenchymal transition and motility in oral cancer cells via induction of IL-6 expression. Oncology Letters. 2025.10; 30 (4): 473. ( PubMed , DOI )2025
• Ibi, H; Inoue, KA; Takahashi, K; Matsumoto, T; Shirouzu, M; Harada, H; Watabe, T. TGF-β promotes progression of squamous cell carcinoma by regulating multiple components of tumor microenvironment CANCER SCIENCE. 2025.01; 116 323.2025
• Yukinori Ikeda, Makoto Kondo, Jun-Ichi Suehiro, Hiroko Oshima, Sau Yee Kok, Kazuki Takahashi, Joris Pauty, Dong Wang, Hiroyuki Sakurai, Tetsuro Watabe, Masanobu Oshima, Yukiko T Matsunaga. A tumor-microvessel on-a-chip reveals a mechanism for cancer cell cluster intravasation. iScience. 2025.06; 28 (6): 112517. ( PubMed , DOI )2025

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