Institute of Science Tokyo · Institute for Advanced Studies · 教授

Research keywords粘膜免疫・樹状細胞・組織幹細胞・マクロファージ

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• Nakagawa S, Sato T, Ohashi E, Kajita M, Miya F, Yamamoto K, Yotsumata H, Yamaguchi K, Nakajima Y, Miura A, Kinugasa Y, and Ohteki T.. An organoid library of human esophageal squamous cell carcinomas (ESCCs) uncovers the chemotherapy-resistant ESCC features Communications Biology. 2025.04; 8 (1): 507. ( DOI )2025
• Kanayama M, Izumi Y, Onai N, Akashi T, Hiraoka Y, Ohteki T.. Diverse developmental pathways of lymphoid conventional dendritic cells with distinct tissue distribution and function Science Advances. 2025.06; 11 (23): eadt4909. ( DOI )2025
• Miwako Sase, Taku Sato, Hajime Sato, Fuyuki Miya, Shicheng Zhang, Hiroshi Haeno, Mihoko Kajita, Tadahide Noguchi, Yoshiyuki Mori, Toshiaki Ohteki. Comparative analysis of tongue cancer organoids among patients identifies the heritable nature of minimal residual disease. Dev Cell. 2025.02; 60 (3): 396-413.e6. ( PubMed , DOI )2025
• Ohara D, Takeuchi Y, Watanabe H, Lee Y, Mukoyama H, Ohteki T, Kondoh G, Hirota K.. Notch2 with retinoic acid license IL-23 expression by intestinal EpCAM+ DCIR2+ cDC2s in mice J Exp Med.. 2024.02; 221 e20230923.2024

• 「オートファジーが腸上皮幹細胞維持と腸再生に必要不可欠なことを発見 」― 腸管障害疾患の治療法開発に期待 ―
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• 新規in vivo 幹細胞競合モデルの創成と分子基盤解明
• 「インターフェロンシグナル制御が腸幹細胞の維持に重要なことを発見」―頑強な腸上皮を保つための新たな仕組み―

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