Institute of Science Tokyo · Institute for Advanced Studies · 准教授

Research keywordsがん免疫・免疫療法・腫瘍微小環境・転移がん

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• Inhibition of fatty acid synthase and induction of apoptosis in human breast cancer cells byCacalia deliphiniifolia
• miR-7 suppresses brain metastasis of cancer stem-like cells by modulating Kruppel-like factor 4 in breast cancer
• Upregulation of lipogenic genes, SREBP-1, ACLY, ACC-1 and FAS, confer proliferation and survival advantages to cancer stem-like cells in ductal carcinoma in situ
• Bone morphogenetic protein 7 in dormancy and metastasis of prostate cancer stem-like cells in bone (vol 19, pg 2641, 2011)

• BMP7 induces dormancy of prostatic tumor stem cell in bone
• ABCタンパク質による脂質恒常性維持機構の解明
• The role of tumor associated macrophage in recurrent growth of tumor stem cell
• 腫瘍関連MUC1を標的とするCAR T細胞療法およびフェロトーシス誘導併用療法の開発

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