Institute of Science Tokyo · Institute for Advanced Studies

Research keywordssingle-cell transcriptomics・RNA splicing kinetics・deep generative models・single-cell survival analysis・hazard modeling・schizophrenia genetics

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• Chikara Mizukoshi, Yasuhiro Kojima, Satoshi Nomura, Shuto Hayashi, Ko Abe, Teppei Shimamura. DeepKINET: a deep generative model for estimating single-cell RNA splicing and degradation rates. Genome Biol. 2024.09; 25 (1): 229. ( PubMed , DOI )2024
• scTREND: An annotation-free single-cell time-resolved and condition-dependent hazard model
• DeepKINET: a deep generative model for estimating single-cell RNA splicing and degradation rates.
• ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk.

• 深層生成モデルと大規模言語モデルを用いた解釈可能な単一細胞摂動効果予測手法の開発

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