Institute of Science Tokyo · Graduate School of Medical and Dental Sciences

Research keywords麻疹ウイルス、膜融合、中枢神経病原性・医学・歯学・薬学・保健

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• Yuichi Hirai, Ryuichi Takemoto, Yusuke Yanagi, Yuta Shirogane. Amino acid changes accumulated in the fusion protein allow neuropathogenic measles viruses to use a broad repertoire of host factors for cell fusion triggering. J Virol. 2025.05; 99 (5): e0230724. ( PubMed , DOI )2025
• Yuta Shirogane, Hidetaka Harada, Yuichi Hirai, Ryuichi Takemoto, Tateki Suzuki, Takao Hashiguchi, Yusuke Yanagi. Collective fusion activity determines neurotropism of an en bloc transmitted enveloped virus. Sci Adv. 2023.01; 9 (4): eadf3731. ( PubMed , DOI )2023
• Ryuichi Takemoto, Yuichi Hirai, Shumpei Watanabe, Hidetaka Harada, Tateki Suzuki, Takao Hashiguchi, Yusuke Yanagi, Yuta Shirogane. Interaction of the Hemagglutinin Stalk Region with Cell Adhesion Molecule (CADM) 1 and CADM2 Mediates the Spread between Neurons and Neuropathogenicity of Measles Virus with a Hyperfusogenic Fusion Protein. J Virol. 2023.05; 97 (5): e0034023. ( PubMed , DOI )2023
• Amino acid changes accumulated in the fusion protein allow neuropathogenic measles viruses to use a broad repertoire of host factors for cell fusion triggering

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