Institute of Science Tokyo · Institute for Advanced Studies

Research keywordsFerroptosis・YAP TAZ Regulation・Iron Metabolism・Cancer Microenvironment・Liver Injury・Lung Cancer

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• Iron accelerates Fusobacterium nucleatum-induced CCL8 expression in macrophages and is associated with colorectal cancer progression.
• Hippo Pathway Drives Durable Non-Cell-Autonomous Ferroptosis Resistance in Lung Cancer.
• Iron overload in CD11c+ myeloid cells exacerbates acetaminophen hepatotoxicity.
• Iron and Bile Acids Synergize to Exacerbate Congenital Cholestatic Liver Injury via Ferroptosis.

• 鉄動態が規定する細胞挙動と胎児血管形成の分子基盤の解明

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