Institute of Science Tokyo · Graduate School of Medical and Dental Sciences · 准教授

Research keywordsoligodendrocyte development・CNS myelination・extracellular matrix proteins・laminin signaling・teneurin-4・oligodendrocyte precursor cells・axon adhesion・myelin formation

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• Rina Kawaguchi, Tsunehiro Miyakoshi, Akira Yoshimoto, Shoichi Hosoya, Yuki Kugii, Takehiko Sasaki, Nobuharu Suzuki, Ryunosuke Ohkawa. Homocysteine thiolactone affects paraoxonase 1 activity via altered paraoxonase 1 distribution on high-density lipoprotein particles. Biosci Rep. 2026.01; ( PubMed , DOI )2026
• Binri Sasaki, Momo Oishi, Tomoka Aoki, Mai Hyodo, Chinami Onchi, Nanako Yamada, Hitomi Misawa, Momona Yamada, Chikako Hayashi, Kiyotoshi Sekiguchi, Keisuke Hamada, Yuji Yamada, Yamato Kikkawa, Motoyoshi Nomizu, Nobuharu Suzuki. Myelin Formation by Oligodendrocytes Is Enhanced Through Laminin-411 and Its Derived Peptide. Glia. 2025.08; 73 (8): 1692-1706. ( PubMed , DOI )2025
• Momona Yamada, Binri Sasaki, Nanako Yamada, Chikako Hayashi, Kohei Tsumoto, Susana de Vega, Nobuharu Suzuki. The pericellular function of Fibulin-7 in the adhesion of oligodendrocyte lineage cells to neuronal axons during CNS myelination Biochem Biophys Res Commun. 2025.02; 748 151271. ( DOI )2025
• 佐々木 敏莉，大野 玲菜，山田 桃奈，山田 渚湖，鈴木 喜晴. 細胞外マトリックス分子によるオリゴデンドロサイトの発生・分化の制御機構 生化学. 2024.04; 96 (2): 296-300.2024

• 髄鞘関連疾患モデルマウスを用いた小径軸索変性の形態学的・生化学的プロファイリング
• 間葉系幹細胞の分化スイッチ制御に関わる遺伝子の解析
• 中枢神経系における小径軸索髄鞘化メカニズムの解明と関連疾患への応用を目指す研究
• 髄鞘形成におけるテニューリン4の機能解明と髄鞘関連疾患への応用を目指す研究

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