Institute of Science Tokyo · Institute for Advanced Studies

Research keywordscircadian clock regulation・primitive streak formation・mevalonate pathway・zebrafish photic signaling・ERK-MAPK signaling・allergen-specific IgE assays・Stevens-Johnson syndrome pharmacogenomics・teratogenicity testing

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• Sachiko Nishina, Satoshi Kofuji, Keiko Matsubara, Hazuki Anzai, Kyoko Hirakata, Yuya Hanazono, Yoshimi Okamoto-Uchida, Jun Hirayama, Nobutoshi Ito, Maki Fukami, Hiroshi Nishina. A novel OPHN1 variant associated with cyclic strabismus but in the absence of OPHN1 syndrome. Sci Rep. 2026.04; 16 (1): ( PubMed , DOI )2026
• Misaki Kosaka*, Yoshimi Okamoto-Uchida*, Haruka Hirose*, Yuya Nagaoka, Norio Miyamura, Akinori Kanai, Daiki Hatakeyama, Michiko Nakagawa, Miki Nishio, Tomohiko Maehama, Akira Suzuki, Yutaka Suzuki, Teppei Shimamura, Hiroshi Nishina. Sustained YAP1 activation induces DNA demethylation that promotes the development of hepatocellular carcinomas lacking driver gene mutations Research Square. 2025.08; ( DOI )2025
• Jing Pu, Satoshi Kofuji, Yoshimi Okamoto-Uchida, Keiko Danzaki, Ruoxing Yu, Akira Suzuki, Satoshi Kitajima and Hiroshi Nishina. Lethal phenotype-based database screening identifies ceramide as a negative regulator of primitive streak formation Stem Cells. 2023;2023
• 小藤 智史、岡本（内田）好海、仁科 博史. 生死を制御するJNKシグナル伝達経路 医学のあゆみ. 2022; 283 (5): 420-424.2022

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