Institute of Science Tokyo · Institute for Advanced Studies · 准教授

Research keywordsbasophils・allergic skin inflammation・atopic dermatitis・NLRP3 inflammasome・monocytes and macrophages・inflammatory responses・acute respiratory distress syndrome・cellular senescence

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• 三宅 健介, 伊藤 潤哉, 烏山 一. 【皮膚を構成する細胞の最新知見】皮膚炎症における好塩基球の役割 皮膚科. 2025.06; 7 (6): 509-517. ( 医中誌 )2025
• 三宅 健介, 伊藤 潤哉. 【最近のトピックス2025 Clinical Dermatology 2025】皮膚疾患の病態 RNA結合蛋白質による好塩基球およびアトピー性皮膚炎の制御 臨床皮膚科. 2025.04; 79 (5): 55-59. ( 医中誌 )2025
• Yoshitaka Gunji, Takayoshi Matsumura, Tadayoshi Karasawa, Takanori Komada, Chintogtokh Baatarjav, Satoko Komori, Hidetoshi Aizawa, Yoshiko Mizushina, Hidetoshi Tsuda, Kensuke Miyake, Takashi Maruyama, Tsukasa Ohmori, Hajime Karasuyama, Masafumi Takahashi. IL-33-primed NLRP3 inflammasome in basophils drives IL-1β production and initiates atopic dermatitis inflammation. Cell Death Discov. 2025.07; 11 (1): 346. ( PubMed , DOI )2025
• Junya Ito, Kensuke Miyake, Tomoki Chiba, Kazufusa Takahashi, Yutaro Uchida, Perry J Blackshear, Hiroshi Asahara, Hajime Karasuyama. Tristetraprolin-mediated mRNA destabilization regulates basophil inflammatory responses. Allergol Int. 2025.04; 74 (2): 263-273. ( PubMed , DOI )2025

• 「 希少な免疫細胞である好塩基球の分化・成熟経路を解明 」 ― アレルギーや寄生虫感染への応用に期待 ―
• Targeting Tristetraprolin in Basophils: A Breakthrough in Allergic Inflammation Treatment
• ヒト好塩基球分化経路の解明
• Pre-basophils: A basophil origin story

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