Institute of Science Tokyo · International Research Institute for Medical-Engineering Collaboration · 准教授

Research keywordsintestinal stem cells・revival stem cells・intestinal monolayers・tumor differentiation・regenerative medicine

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• Sakura Kirino, Fumiya Uefune, Kensuke Miyake, Nobuhiko Ogasawara, Sakurako Kobayashi, Satoshi Watanabe, Yui Hiraguri, Go Ito, Keiichi Akahoshi, Daisuke Ban, Johan H van Es, Hans Clevers, Mamoru Watanabe, Ryuichi Okamoto, Shiro Yui. Fetal reversion from diverse lineages sustains the intestinal stem cell pool and confers stress resilience. Commun Biol. 2026.01; ( PubMed , DOI )2026
• 油井 史郎、桐野 桜、上船 史弥. 腸における復活幹細胞とその病理学的意義 Bio Clinica. 2026.05; 41 (5): 55-58.2026
• 油井 史郎、桐野 桜、上船 史弥. 腸における復活幹細胞とその病理学的意義 Precision Medicine. 2026.05; 9 (5): 74-77.2026
• Fumiya Uefune, Shiro Yui. A murine small intestinal two-dimensional monolayer platform that induces fate commitment toward a revival stem cell state. Biochem Biophys Res Commun. 2026.03; 814 153645. ( PubMed , DOI )2026

• ヒト体外複合臓器モデルによる生体維持機構解析
• 腸オルガノイドによる大腸組織再生の最適化
• 原腸由来臓器の上皮細胞可塑性と互換性の検証
• 上皮傷害関連リプログラムにおける分子機序の解明

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