Institute of Science Tokyo · Graduate School of Medical and Dental Sciences · 准教授

Research keywordsFLT3-ITD acute myeloid leukemia・proteasome-associated deubiquitinases・STAT5-PIM-mTOR signaling・PI3K and AKT inhibitor resistance・diffuse large B-cell lymphoma・primary vitreoretinal lymphoma・hematologic immunotherapy・CAR-T Toxicity

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• Nogami, A; Amemiya, HJ; Fujiwara, H; Umezawa, Y; Tohda, S; Nagao, T. Targeting USP14/UCHL5: A Breakthrough Approach to Overcoming Treatment-Resistant FLT3-ITD-Positive AML INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2024.10; 25 (19): ( PubMed , DOI )2024
• Keisuke Tanaka, Ayako Ichikawa, Natsuka Umezawa, Kouhei Yamamoto, Kota Yoshifuji, Keigo Okada, Ayako Nogami, Yoshihiro Umezawa, Toshikage Nagao, Chizuko Sakashita, Takehiko Mori, Shuji Tohda, Ryuji Koike, Shinsuke Yasuda, Masahide Yamamoto. Lymphoproliferative disorder risk after methotrexate treatment for rheumatoid arthritis. Cancer Sci. 2023.09; 114 (9): 3719-3727. ( PubMed , DOI )2023
• Motomura, Y; Yoshifuji, K; Tachibana, T; Takase, H; Arai, A; Tanaka, K; Okada, K; Nogami, A; Umezawa, Y; Sakashita, C; Yamamoto, M; Mori, T; Nagao, T. Clinical factors for central nervous system progression and survival in primary vitreoretinal lymphoma BRITISH JOURNAL OF HAEMATOLOGY. 2023.12; ( PubMed , DOI )2023
• 厚井 聡志, 野上 彩子, 藤原 煕基, 坂東 夏菜, 齊藤 真貴子, 長田 有生, 田中 圭祐, 坂下 千瑞子, 吉藤 康太, 岡田 啓五, 梅澤 佳央, 長尾 俊景, 山本 正英, 森 毅彦. 無症候性の脳出血を認めた急性前骨髄球性白血病 臨床血液. 2023.11; 64 (11): 1426-1430. ( 医中誌 )2023

• 骨髄不全症における標的オトリ人工抗体開発に向けたネオエピトープ反応性T細胞の検出
• 難治性白血病の活性化チロシンキナーゼ特異的ユビキチンプロテアソーム系と耐性化
• 体細胞の遺伝子構造に基づくPNHクローンの抗原提示機構の解明

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