Institute of Science Tokyo · Institute for Advanced Studies · 特任助教

Research keywords血液・iPS細胞・がん代謝・血管

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• Stabilization of fatty acid synthesis enzyme acetyl-CoA carboxylase 1 suppresses acute myeloid leukemia development
• Generation of human induced pluripotent stem cell lines derived from four Rett syndrome patients with MECP2 mutations
• Myeloid leukemia factor 1 stabilizes tumor suppressor C/EBPα to prevent Trib1-driven acute myeloid leukemia.
• Generation of human induced pluripotent stem cell lines derived from two glucose transporter 1 deficiency syndrome patients

• ヒトVHL病治療法探索に向けた血管オルガノイドの移植ヒト化マウスモデルの開発
• 造血前駆細胞から白血病幹細胞への転換機構の解明
• 造血前駆細胞から白血病幹細胞への転換にお けるエネルギー代謝機構の解明
• ヒト多能性幹細胞由来の動静脈腫瘍血管モデルの開発と新規治療戦略の創出

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