Institute of Science Tokyo · Institute for Advanced Studies · 教授

Research keywords多能性幹細胞・オルガノイド・iPS細胞・感染症・臓器チップ・ウイルス・創薬

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• Miguel Martí, Alba Cano-Vicent, Mercedes Cervera-Alamar, Rina Hashimoto, Kazuo Takayama, Ángel Serrano-Aroca. Multifunctional materials with potential antiviral applications in face masks, face shields, and hydrogels against mpox virus. Sci Rep. 2025.09; 15 (1): 32075. ( PubMed , DOI )2025
• Shuhei Tsujino, Masumi Tsuda, Naganori Nao, Kaho Okumura, Lei Wang, Yoshitaka Oda, Yume Mimura, Jingshu Li, Rina Hashimoto, Yasufumi Matsumura, Rigel Suzuki, Saori Suzuki, Kumiko Yoshimatsu, Miki Nagao, Jumpei Ito, Kazuo Takayama, Kei Sato, Keita Matsuno, Tomokazu Tamura, Shinya Tanaka, Takasuke Fukuhara, . Evolution of BA.2.86 to JN.1 reveals that functional changes in non-structural viral proteins are required for fitness of SARS-CoV-2. J Virol. 2025.09; e0090825. ( PubMed , DOI )2025
• Kazuo Takayama, Daiju Yamazaki. [Preface]. Nihon Yakurigaku Zasshi. 2025; 160 (2): 86. ( PubMed , DOI )2025
• Yuki Kitai, Shohei Kojima, Aikeda Aishajiang, Miyuki Kawase, Oshi Watanabe, Haruka Yabukami, Rina Hashimoto, Yukiko Akahori, Hiroshi Katoh, Kazuo Takayama, Hidekazu Nishimura, Kazuya Shirato, Makoto Takeda. Changes in ORF4 of HCoV-229E under different culture conditions. J Gen Virol. 2025.07; 106 (7): ( PubMed , DOI )2025

• 創薬応用を目指した高純度CYP3A4発現ヒトES/iPS由来肝細胞の作製法の開発
• 光照射により任意の組織においてゲノム編集・遺伝子発現操作する技術の開発
• 生体模倣デバイスを用いた腸運動異常を起点とする炎症スバイラルの解析
• 次世代の医療を開拓するヒト小腸組織チップの開発と応用

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