Tokyo University of Pharmacy and Life Sciences · Department of Pharmacy / Faculty of Pharmaceutical Sciences

Research keywordsDHODH・trophoblast invasion・syncytialization・decidualization・endometriosis・cellular senescence・prostaglandin signaling・oxidative stress・quercetin・riboflavin

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• DHODH inhibition impairs mitochondrial function and extravillous trophoblast invasion: Protective roles of quercetin and riboflavin2026 · Journal of Pharmacological Sciences
• Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence2026 · FEBS Open Bio
• Loss of miR-424 and miR-503 promotes decidualization of human endometrial stromal cells by increasing SCARA5 expression.2025 · Medical molecular morphology
• Heat stress induces oxidative stress and activates the KEAP1‐NFE2L2‐ARE pathway in reproduction‐related cells2025 · Animal Science Journal

• 細胞内エネルギー代謝系に着眼したウシ胎盤細胞分化メカニズム解明と機能同定2024 · 科学研究費助成事業
• 精子と受精卵の自然免疫受容体TLR2によるウシ母体の受胎に向けた免疫寛容増幅機構2023 · 科学研究費助成事業
• 新規ゲノム内在性因子による妊娠高血圧症候群の病態解明への挑戦2023 · 科学研究費助成事業
• ウシ栄養膜細胞の胎盤構成細胞への分化機構の解析2022 · 科学研究費助成事業 基盤研究(B)

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