Tokyo University of Pharmacy and Life Sciences · School of Life Sciences · 助教

Research keywordsoligodendrocyte differentiation・Schwann cell biology・hypomyelinating leukodystrophy・diabetic neuropathy・ER stress・reactive oxygen species・neurite outgrowth・ELMO1 signaling・mitochondrial respiration・neurodevelopmental disorders

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• Hesperetin, Acting Through Inhibition of c-Jun Signaling, Mitigates Hypomyelinating Disease-Associated Stop-Loss Claudin-11-Induced Defective Morphogenesis in Oligodendroglial FBD-102b Cells2026 · International Journal of Molecular Sciences
• The RhoG-Binding Domain of ELMO1 Rescues the PTENopathy-like Phenotype in Oligodendroglial FBD-102b Cells2026 · International Journal of Molecular Sciences
• Imeglimin improves hyperglycemia and hypoglycemia-induced cell death and mitochondrial dysfunction in immortalized adult mouse Schwann IMS32 cells.2025 · Journal of diabetes investigation
• The ErbB2–Dock7 Signaling Axis Mediates Excessive Cell Morphogenesis Induced by Autism Spectrum Disorder- and Intellectual Disability-Associated Sema5A p.Arg676Cys2025 · International Journal of Molecular Sciences

• ピルビン酸投与による糖尿病性神経障害改善メカニズムの解明2024 · 2024年度研究助成 (精神・神経・脳領域)
• ミトコンドリア機能改善を介した糖尿病性神経障害治療法の開発2022 · 令和4年度共同利用・共同研究課題
• 糖尿病性神経障害に対する外因性ピルビン酸の有用性2021 · 令和３年度共同利用・共同研究課題
• 外因性ピルビン酸欠乏により誘導される細胞死のグルコース代謝異常の分子機序の解明2020 · 科学研究費助成事業 若手研究

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