Tottori University · Faculty of Medicine, Department of Medicine · 准教授

Research keywordsoncolytic vaccinia virus・tumor immunology・IL-7・IL-12・CD8 T cells・pancreatic cancer・ovarian cancer

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• Oncolytic vaccinia virus induces a novel phenotype of CD8+ effector T cells characterized by high ICOS expression2021
• IL-7 coupled with IL-12 increases intratumoral T cell clonality, leading to complete regression of non-immunogenic tumors2021
• Fusogenic oncolytic vaccinia virus enhances systemic antitumor immune response by modulating the tumor microenvironment2021
• Anti-Tumor Effects of MAPK-Dependent Tumor-Selective Oncolytic Vaccinia Virus Armed with CD/UPRT against Pancreatic Ductal Adenocarcinoma in Mice2021

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