University of Tsukuba · Faculty of Medicine · 助教

Research keywordsグリオーマ幹細胞・造血発生・造血幹細胞の増幅・遺伝子治療

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• A more efficient method for generating glioblastoma-multiforme model in mice using genome editing technology
• Induction of tumor-initiating cells and glioma-initiating cells from fetal neural stem cells through p53 genome editing
• Chemical Screening Identifies EUrd as a Novel Inhibitor Against Temozolomide-Resistant Glioblastoma-Initiating Cells
• Ceacam1L Modulates STAT3 Signaling to Control the Proliferation of Glioblastoma-Initiating Cells

• Functional analysis of HIPK2 in the differentiation of vascular endothelial progenitor cell into hematopoietic stem cells
• ナノ秒パルス高電界（nsPEF）およびバースト正弦波高電界(IBSEF)を用いた血球前駆細胞の分化制御
• 胎生期マウスの造血系構築におけるHIPK2の作用点の解明
• ゲノム編集を用いたEva1陽性グリオーマ幹細胞の増殖抑制ベクターの開発

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