Tokyo University of Agriculture and Technology · Graduate School of Agriculture / Faculty of Agriculture Research Division / Faculty of Agriculture · 准教授

Research keywordsAspergillus oryzae・糸状菌・麹菌・タンパク質生産・遺伝子発現制御・codon optimization・小胞体ストレス応答・filamentous fungi

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• Improved α-Amylase Production by Dephosphorylation Mutation of CreD, an Arrestin-like Protein Required for Glucose-induced Endocytosis of Maltose Permease and Carbon Catabolite De-repression in Aspergillus oryzae.2017 · Applied and environmental microbiology
• Glucose-induced endocytic degradation of the maltose transporter MalP is mediated through ubiquitination by the HECT-ubiquitin ligase HulA and its adaptor CreD in Aspergillus oryzae
• Distinct mechanism of activation of two transcription factors, AmyR and MalR, involved in amylolytic enzyme production in Aspergillus oryzae
• Cellular responses to the expression of unstable secretory proteins in the filamentous fungus Aspergillus oryzae.

• 糸状菌におけるグルコースキナーゼによる酵素タンパク質生産制御機構の解析
• 生分解かつバイオマス由来新規プラスチックの農業用フィルム等開発および実用化実証事業
• mRNA分解と小胞体ストレス応答のクロストークによる小胞体恒常性維持機構
• ヒト小腸における8,400種類ジ・トリペプチド吸収基盤の解明

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