Tokyo University of Agriculture and Technology · Graduate School of Agriculture / Faculty of Agriculture Research Division / Faculty of Agriculture · 教授

Research keywordsβ-フルクトフラノシダーゼ・α-グルコシダーゼ・アミラーゼ・オリゴ糖・セルラーゼ・バイオマス・糖質関連酵素

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• Purification, crystallization and preliminary X-ray analysis of an HA17–HA70 (HA2–HA3) complex from Clostridium botulinum type C progenitor toxin
• Traffic of botulinum toxin complex: the crystal structure and the role of toxin complex.
• Construction of chimeric cyclodextrin glucanotransferases from Bacillius circulans A11 and Paenibacillus macerans IAM1243 and analysis of their product specificity
• Studies on the hydrolyzing mechanism for cyclodextrins of Thermoactinomyces vulgaris R-47 alpha-amylase 2 (TVAII). X-ray structure of the mutant E354A complexed with beta-cyclodextrin, and kinetic analyses on cyclodextrins

• 澱粉に作用する新規マルチドメイン糖転移酵素の構造機能相関と糖認識機構の解明
• 重症型ブドウ球菌感染症の成立に関わる外毒素の基質認識機構の解明と予防戦略
• 重症型ブドウ球菌感染症の成立に関わる外毒素の基質認識機構の解明と予防戦略
• ヘパリチナーゼの耐熱化にもとづく簡便で実用的な分子設計法の確立

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