Tokyo University of Agriculture and Technology · Graduate School of Engineering / Institute of Engineering · 准教授

Research keywordsolfactory receptors・yeast biosensors・odor sensing・GPCR functional expression・bioluminescence assays・odor perception・encapsulin proteins

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• Modification of the response of olfactory receptors to acetophenone by CYP1a2
• Split luciferase complementation assay for the analysis of G protein-coupled receptor ligand response in Saccharomyces cerevisiae
• The N-terminal replacement of an olfactory receptor for the development of a Yeast-based biomimetic odor sensor
• Vapor detection and discrimination with a panel of odorant receptors expressed in heterologous cells

• 嗅覚の多様性を司る嗅覚受容体の細胞膜輸送機構解明
• がん幹細胞の嗅覚受容体選択的発現機構およびその意義の解明
• 難溶性ペプチド群から医薬品を発掘する溶媒「双性イオン液体」の開発
• 新規アクセサリータンパク質の導入による嗅覚受容体の機能活性化

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