University of Shizuoka · Graduate School of Pharmaceutical Sciences / Faculty of Pharmaceutical Sciences · 教授

Research keywordsてんかん治療・抗がん薬・物理系薬剤学・臨床薬物動態学・認知症治療

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• Combined antitumor effect of cyclophosphamide and bromodeoxyuridine in BDF1 mice bearing L1210 ascites tumors
• Pharmacokinetic and Pharmacodynamic Analysis of Acetylcholinesterase Inhibition by Distigmine Bromide in Rats
• Evaluation of the pharmacokinetic interaction of midazolam with ursodeoxycholic acid, ketoconazole and dexamethasone by brain benzodiazepine receptor occupancy
• Development of Rapid Genotyping Methods for Single Nucleotide Polymorphisms of Cytochrome P450 2C9 (CYP2C9) and Cytochrome P450 2C19 (CYP2C19) and Their Clinical Application in Pediatric Patients with Epilepsy

• 臨床症例に基づく抗てんかん薬の薬物相互作用発現様式の解明
• 認知症患者の行動・心理症状の改善を目的とした治療薬の薬物動態・薬効解析
• オレキシン受容体拮抗薬の精密投与設計を目指した体内動態影響因子の多面的解析
• 第3世代抗てんかん薬の精密投与設計を目指した薬物動態影響因子の多面的解析

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