University of Shizuoka · Graduate School of Pharmaceutical Sciences / Faculty of Pharmaceutical Sciences · 助教

Research keywordsサイトカイン・免疫寛容・粘膜免疫・自然免疫

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• ASC-deficiency impairs host defense against Aeromonas hydrophila infection in Japanese medaka, Oryzias latipes.
• Characterization and expression analysis of tandemly-replicated asc genes in the Japanese medaka, Oryzias latipes.
• Identification and expression of phospholipase A2 genes related to transcriptional control in the interleukin-17A/F1 pathway in the intestines of Japanese medaka Oryzias latipes.
• Efficacy of dietary fermented vegetable product on immune response, up-regulation of immune-related genes and protection of kuruma shrimp (Marsupenaeus japonicus) against Vibrio parahaemolyticus

• 出生早期の小腸に特異的に存在する腸上皮細胞LREsの免疫寛容制御における重要性
• 魚類腸管におけるインターロイキン１７を介した抗菌分子産生機構の解明
• カプサイシン-TRPV1シグナルを介した経口免疫寛容成立メカニズムの解明

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