University of Shizuoka · Graduate School of Pharmaceutical Sciences / Faculty of Pharmaceutical Sciences · 講師

Research keywordsmucosal immunology・secretory IgA・Listeria infection・GPR signaling・dendritic cells・plant-made antibodies

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• Pyruvate-GPR31 axis induces LysoDC dendrite protrusion to M-cell pockets for effective immune responses.2025
• GPR35 mediates monocyte recruitment to the sites of Listeria monocytogenes infection2025
• Prevention of Shiga toxin 1-caused colon injury by plant-derived recombinant IgA2022
• Plant-derived secretory component gives protease-resistance to Shiga toxin 1-specific dimeric IgA2021

• 腸内細菌由来の代謝物による腸血管のバリア機能の制御機構の解明2022
• 複数の病原体を標的とした分泌型IgAイムノアドヘシンの植物での生産2019
• 広範な食中毒に適応可能な分泌型IgAイムノアドヘシンの作製と植物での生産2016
• 実用植物が作る志賀毒素特異的分泌型ＩｇＡ植物抗体の毒素中和作用と安全性の研究2015

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