University of Shizuoka · Graduate School of Pharmaceutical Sciences / Faculty of Pharmaceutical Sciences · 助教

Research keywordscancer extracellular vesicles・photodynamic therapy・angiogenic vessels・phosphoinositide profiling・liposomal drug delivery・lymphoma drug resistance・tumor microenvironment

Research fieldsCell biology・Tumor biology・薬物送達学

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• Quantification and Imaging of Exosomes via Luciferase-Fused Exosome Marker Proteins: ExoLuc System
• A mass spectrometric method for in-depth profiling of phosphoinositide regioisomers and their disease-associated regulation
• Sensitive and rapid quantification of exosomes by fusing luciferase to exosome marker proteins
• In vivo imaging of long-term accumulation of cancer-derived exosomes using a BRET-based reporter

• 好中球のMDEVsを利用したDDSの開発と脳梗塞治療への応用
• 腫瘍集積性希少シアル酸を利用した新規がん検出蛍光プローブの開発
• 生体イメージングに基づいたがん細胞外小胞EVsの病態機能解析
• シアリダーゼ活性に着目したマイコプラズマ検出系の確立とマイコプラズマ感染がんにおけるシアリダーゼの機能解析

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