The University of Tokyo · Graduate School of Agricultural and Life Sciences / Faculty of Agriculture · 教授

Research keywords二次代謝産物・合成生物学・生合成・構造生物学・放線菌

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• QM/MM Study of the Catalytic Mechanism and Substrate Specificity of the Aromatic Substrate C-Methyltransferase Fur62024
• Crystal structure of tetrameric homoisocitrate dehydrogenase from an extreme thermophile, Thermus thermophilus: Involvement of hydrophobic dimer-dimer interaction in extremely high thermotolerance
• Involvement of subdomain II in the recognition of acetyl-CoA revealed by the crystal structure of homocitrate synthase from Sulfolobus acidocaldarius.
• Structure and Mechanism of the Monoterpene Cyclolavandulyl Diphosphate Synthase that Catalyzes Consecutive Condensation and Cyclization

• テルペン-ポリケタイド融合化合物ナフテルピンの生合成
• イソプレンユニット生合成経路を標的とした抗菌剤と抗マラリア剤開発のための探索研究
• テルペンーポリケタイド融合化合物ナフテルピンの生合成
• 放線菌の生産する新規17員環マクロサイクリック化合物の生合成研究

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