The University of Tokyo · Institute for Quantitative Biosciences · 教授

Research keywordsmolecular genetics・intracellular trafficking・meiotic arrest・genome demethylation・protein aggregation・JC virus

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• Hydrocephalus, situs inversus, chronic sinusitis, and male infertility in DNA polymerase lambda-deficient mice: possible implication for the pathogenesis of immotile cilia syndrome.
• Understanding paternal genome demethylation through live-cell imaging and siRNA
• New allele of mouse DNA/RNA helicase senataxin causes meiotic arrest and infertility
• Role of Jhdm2a in regulating metabolic gene expression and obesity resistance.

• シングルセル解析によるヒト精子エピゲノムプロフィール多様性の検討
• 雌雄配偶子形成における核輸送分子の新機能探索と不妊症発症機序解明
• 精子残存ヒストンの機能と経世代効果の検討
• DNAの物性から理解するゲノムモダリティ

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