The University of Tokyo · Graduate School of Frontier Sciences · 特任助教

Research keywordsmitochondrial RNA modification・tRNA methyltransferases・toxin-antitoxin systems・tRNA cleavage toxins・terminal uridylyltransferases・aminoacyl-tRNA acetylation・bacterial competition・structural biology of RNA enzymes

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• The tRNA pseudouridine synthase TruB1 regulates the maturation of let‐7 miRNA
• Substrate specificity of Mycobacterium tuberculosis tRNA terminal nucleotidyltransferase toxin MenT3.
• Structure of the Caenorhabditis elegans m6A methyltransferase METT10 that regulates SAM homeostasis.
• Function and Regulation of Human Terminal Uridylyltransferases.

• RNA修飾酵素による特異的なmiRNA発現制御の分子基盤解明
• RNA修飾酵素によるマイクロRNA発現制御の分子基盤解明
• アミノアシルtRNAを標的とする毒素の分子機構

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