The University of Tokyo · Graduate School of Engineering / Faculty of Engineering · 助教

Research keywordsPolycomb group proteins・neural precursor cells・astrocyte fate transition・mitochondria-ER contact sites・synaptic plasticity・pyroptosis morphology・histone modifications・neocortical development

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• A morphology and secretome map of pyroptosis
• Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition.
• New insights into the regulation of synaptic transmission and plasticity by the endoplasmic reticulum and its membrane contacts.
• Analysis of histone modifications in mouse neocortical neural progenitor-stem cells at various developmental stages.

• オルガネラ間接触部位における糖脂質分解経路依存的な軸索発達メカニズムの解明
• 単一スパイン内のオルガネラダイナミクス解析に基づく神経変性疾患の発症要因の解明
• 細胞小器官の動態が大脳皮質ニューロンの軸索投射制御に果たす役割の解明
• 医療分野国際科学技術共同研究開発推進事業

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