The University of Tokyo · Graduate School of Medical Sciences / Faculty of Medicine · 講師

Research keywordsatherosclerosis・cholesterol ester hydrolase・macrophage apoptosis・endoplasmic reticulum stress・oxysterols・prostanoid FP receptor・adipogenesis・adrenal enlargement

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• Sterol Regulatory Element-Binding Protein-1 Determines Plasma Remnant Lipoproteins and Accelerates Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice
• Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis
• Targeting of neutral cholesterol ester hydrolase to the endoplasmic reticulum via its N-terminal sequence
• Neutral Cholesterol Ester Hydrolase is Essential for Cholesterol Removal in Human Macrophages and Atherosclerosis

• 腸管上皮が高齢者耐糖能障害に与える影響の解明
• グルコースによる腸管上皮幹細胞制御機構とその疾患との関わりの解明
• 長寿遺伝子SIRT1による腸管を介した糖代謝制御機構の解明

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