The University of Tokyo · Institute for Quantitative Biosciences · 教授

Research keywordsPD-1 signaling・LAG-3 signaling・T-cell inhibition・immune checkpoints・autoreactive T cells・TCR signaling・anti-cancer immunity・autoimmunity control

This is a public-data preview. Personalized fit, contact angles, and saved workflows require sign-in.

• PD-1 agonism by anti-CD80 inhibits T cell activation and alleviates autoimmunity.2022
• Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity.2022
• PD-1 preferentially inhibits the activation of low-affinity T cells.2021
• LAG-3: from molecular functions to clinical applications.2020

• 免疫シナプスの時空間ダイナミクス解析による免疫補助受容体の機能解明2022
• 免疫とがんを支配するシンギュラリティ細胞の解明2018

• Official profile