The University of Tokyo · Graduate School of Frontier Sciences · 准教授

Research keywordsBar・Lim1・Notch・aristaless・hedgehog・trachealess・エンハンサー・クチクラ

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• Requirements of DFR1/heartless, a mesoderm-specific Drosophila FGF-receptor, for the formation of heart, visceral and somatic muscles, and ensheathing of longitudinal axon tracts in CNS
• IDENTIFICATION OF A DIFFERENT-TYPE HOMEOBOX GENE, BARH1, POSSIBLY CAUSING BAR (B) AND OM(1D) MUTATIONS IN DROSOPHILA
• Fate determination of Drosophila leg distal regions by trachealess and tango through repression and stimulation, respectively, of Bar homeobox gene expression in the future pretarsus and tarsus
• Identification of engrailed promoter elements essential for interactions with a stripe enhancer in Drosophila embryos

• 肢形成の分子機構と関連シグナル伝達遺伝子の探索
• 付属肢の進化・多様性の分子メカニズム
• ホメオボックス遺伝子の二段階転写調節による肢芽の区画化と遠近軸形成
• 新たな領域形成における領域特異的転写因子の発現制御と細胞増殖制御の相互作用

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