The University of Tokyo · Graduate School of Medical Sciences / Faculty of Medicine · 助教

Research keywordsgene-environment interactions・polygenic scores・genome-wide association studies・biobank meta-analysis・drug discovery genomics・type 2 diabetes genetics・autoimmune disease genetics・cross-ancestry analysis・blood DNA virome

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• A practical guideline of genomics-driven drug discovery in the era of global biobank meta-analysis
• Gastrointestinal symptoms in COVID-19 and disease severity: a Japanese registry-based retrospective cohort study
• Germline variants and mosaic chromosomal alterations affect COVID-19 vaccine immunogenicity
• Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts.

• 心血管疾患の遺伝子–環境相互作用解明によるゲノム個別化医療と創薬
• 遺伝子–環境相互作用の学術・オミクス横断による個別化医療の実装
• 深層学習によるヒト脂質代謝の遺伝的基盤全体像の解明
• 遺伝子変異の機能性スペクトラム統一的解析と次世代創薬連携による創薬シーズ導出

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