The University of Tokyo · Graduate School of Agricultural and Life Sciences / Faculty of Agriculture · 准教授

Research keywords放線菌・酵素・生合成・微生物・二次代謝産物

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• Corrigendum to: Biosynthetic Gene Cluster for Surugamide A Encompasses an Unrelated Decapeptide, Surugamide F (ChemBioChem, (2016), 17, 18, (1709-1712), 10.1002/cbic.201600350)
• α位に置換基を持つアミノ酸を利用する非リボソームペプチド生合成系の機能解析
• Identification and Analysis of the Biosynthetic Gene Cluster for the Hydrazide-Containing Aryl Polyene Spinamycin
• Regio- and stereospecific hydroxylation of various steroids at the 16α position of the D ring by the Streptomyces griseus cytochrome P450 CYP154C3.

• ユニークな骨格を持つ放線菌由来二次代謝産物の生合成経路の解明
• チオテンプレート酵素の持つ生合成機構の精密機能解析
• 合成生物学的手法を利用した人工生合成経路設計技術の開発
• 非リボソームペプチド合成酵素の触媒機能の精密解析

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