The University of Tokyo · Institute of Medical Science · 教授

Research keywordsMolecular Biology・Gene Therapy・Neurosurgery・Oncology・分子生物学

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• Expression of human GNE through adeno-associated virus mediated therapy delays progression of myopathy in the DMRV/hIBM mouse model
• DOK7 gene therapy enhances motor activity and life span in ALS model mice
• Stability Evaluation of rAAV Serotype 1, 2, 8,9 and Wild-Type AAV2 Under Various Conditions
• LONRF2 is a protein quality control ubiquitin ligase whose deficiency causes late-onset neurological deficits.

• AAV中空粒子を用いる臓器特異的DDSの臨床応用に向けた開発
• 超音波血液脳関門開放とAAVベクターを用いた成体マーモセットてんかんモデルの開発
• Vector Development for Gene Therapy
• 神経幹細胞への染色体部位特異的遺伝子組込み法の開発

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