The University of Tokyo · Graduate School of Frontier Sciences · 教授

Research keywordsクライオ電子顕微鏡・X線結晶構造解析・B型肝炎ウイルス・自然免疫・シグナル伝達・構造生物学・ウイルス感染

This is a public-data preview. Personalized fit, contact angles, and saved workflows require sign-in.

• Small-Molecule TLR8 Antagonists via Structure-Based Rational Design.
• Targeting toll-like receptor 7 as a therapeutic development strategy for systemic lupus erythematosus.
• TLR4-MD-2 complex is negatively regulated by an endogenous ligand, globotetraosylceramide.
• Toward a structural understanding of nucleic acid-sensing Toll-like receptors in the innate immune system.

• 核酸認識TLR受容体の構造生物学的研究
• リポクオリティとTLR活性化機構の解析
• 芳香族炭化水素受容体によるダイオキシン認識の構造基盤の解明
• 多階層解析による脂質二重膜中でのToll様受容体の活性化機構の全貌解明

• Official profile