The University of Tokyo · Research Center for Advanced Science and Technology · 特任助教

Research keywordsFGFR aptamers・synthetic receptor systems・signal transduction engineering・antibody affinity maturation・phosphoproteomics・EGFR signaling・single-cell proteomics・molecular imaging probes

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• Characterization of a DNA Aptamer with High Specificity toward Fibroblast Growth Factor Receptor 1
• Spatiotemporal Proteomics Deciphers Functional Selectivity of EGFR ligands
• An epitope‐directed antibody affinity maturation system utilizing mammalian cell survival as readout
• An Engineered Synthetic Receptor–Aptamer Pair for an Artificial Signal Transduction System

• 光学DNAシーケンサービーズが実現するタンパク質機能の大規模評価
• 脂肪酸代謝創生学に資する解析基盤の開発
• Fv界面への変異導入による抗体アゴニスト活性調節方法の開発
• 「培養条件を記録する微小ゲルカプセル」が実現する細胞分化誘導条件の大規模探索

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