The University of Tokyo · Institute for Quantitative Biosciences · 特任教授

Research keywordsion pump・結晶化・膜蛋白質・membrane proteins・structural biology

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• Cryoelectron microscopy of Na+,K+-ATPase in the two E2P states with and without cardiotonic steroids.
• Neutral Phospholipids Stimulate Na,K-ATPase Activity A SPECIFIC LIPID-PROTEIN INTERACTION
• Binding of cardiotonic steroids to Na+,K+-ATPase in the E2P state.
• Crystal structure of the sodium-potassium pump at 2.4 angstrom resolution

• 異なった生理的条件下の筋小胞体カルシウムATPaseの三次元構造解析
• 閃光光分解と氷包埋低温電子顕微鏡による生体反応の時間分解三次元構造解析
• 膜蛋白質結晶中の脂質二重膜の可視化技術の開発
• P型ATPaseによる能動輸送とその制御機構の構造生物学

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