The University of Tokyo · Graduate School of Agricultural and Life Sciences / Faculty of Agriculture · 教授

Research keywordsfood allergy・oral tolerance・dendritic cells・probiotic intervention・glycaemic control・regulatory T cells・prediabetes・immunomodulation

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• The constitutive presence of commensal bacteria contributes to the abundance of cecal IgG2b+ B cells and the supply of serum IgG2b reactive to commensal bacteria in adult mice2025
• Excessive IL-4 environment enhances osteoclastogenesis and modulates inflammatory cell differentiation in bone loss associated with food allergic enteropathy.2025
• Ingestion of egg white after acquisition of oral tolerance with heated egg white in OVA-sensitized mice caused severe allergic symptoms.2025
• Lactococcus lactis subsp. cremoris YRC3780 modifies function of mesenteric lymph node dendritic cells to modulate the balance of T cell differentiation inducing regulatory T cells.2024

• 核移植クローン技術に基づく免疫応答・疾患発症機構の包括的研究基盤2022
• 小腸における食品・共生菌・代謝物の免疫細胞への協調作用からの炎症抑制機構の解明2022
• 免疫研究バイオリソースとしてのT細胞クローンマウスの有用性2019
• 食品による腸管免疫系を介した加齢性炎症および脂肪組織における慢性炎症の制御2018

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