The University of Tokyo · Graduate School of Science / Faculty of Science · 准教授

Research keywordsバイオイメージング・ケミカルバイオロジー・蛍光タンパク質・蛍光プローブ・進化分子工学

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• Red fluorescent scaffold for highly sensitive protease activity probes
• Development of a highly selective fluorescence probe for alkaline phosphatase
• Detection of NAD(P)H-dependent enzyme activity by time-domain ratiometry of terbium luminescence
• Design and synthesis of highly sensitive fluorogenic substrates for glutathione S-transferase and application for activity imaging in living cells

• ケミカルバイオロジー的方法論を活用した『人工ビオチン』誘導体の開発と応用
• Massive Expansion of the Palette of Fluorescent Protein-based Sensors for Multiplexed Imaging of Signaling and Metabolism
• 蛍光プローブ・デンドリマー複合体の創製と、細胞および動物個体イメージングへの応用
• 進化工学と有機合成の融合による革新的蛍光プローブの開発

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