The University of Tokyo · Graduate School of Medical Sciences / Faculty of Medicine · 助教

Research keywordscell reprogramming・pluripotency・DNA methylation・alternative splicing・in vivo reprogramming・chromatin regulation・germ cell tumor models

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• Human Pluripotent Stem Cell-Derived Tumor Model Uncovers the Embryonic Stem Cell Signature as a Key Driver in Atypical Teratoid/Rhabdoid Tumor.
• MYCL-mediated reprogramming expands pancreatic insulin-producing cells.
• Exploring the potential of in vivo reprogramming for studying embryonic development, tissue regeneration, and organismal aging
• NF-κB dynamics determine the stimulus specificity of epigenomic reprogramming in macrophages

• ヒストン・レベルの減衰を原因とする老化表現型とそのメカニズムの解析2026
• 細胞の運命転換における選択的スプライシング制御機構の解析
• ヒストン・レベルの減衰と老化
• エピジェネティックなDNA損傷履歴蓄積と老化

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